In the United States, clobetasol propionate has several brand
Clobevate / Clobex / Cormax / Embeline / Olux / Temovate
Clobetasol propionate ointment Pharmaceutical Raw Materials Best
Generic Name: Clobetasol propionate
Dosage Form: ointment
What Is Clobetasol?
Clobetasol propionate is a high-dose corticosteroid medication that
can be used to reduce pain and itching from skin conditions like
psoriasis. The medication must be prescribed by a doctor and used
as directed. It’s available as a cream, ointment, gel, spray, foam,
lotion, and shampoo. The form you’re prescribed and the amount of
times you’re told to apply it depends on how severe your psoriasis
is. Follow instructions given by your doctor and on the
Clobetasol propionate gel, cream and ointment contain the active
compound Clobetasol propionate, a synthetic corticosteroid, for
topical dermatologic use. Clobetasol, an analog of prednisolone,
has a high degree of glucocorticoid activity and a slight degree of
Indications and Usage for Clobetasol
Clobetasol propionate gel, cream and ointment are super-high
potency corticosteroid formulations indicated for the relief of the
inflammatory and pruritic manifestations of corticosteroid
responsive dermatoses. Treatment beyond 2 consecutive weeks is not
recommended, and the total dosage should not exceed 50 g per week
because of the potential for the drug to suppress the
hypothalamic-pituitary-adrenal (HPA) axis. Use in pediatric
patients under 12 years of age is not recommended. As with other
highly active corticosteroids, therapy should be discontinued when
control has been achieved. If no improvement is seen within 2
weeks, reassessment of the diagnosis may be necessary.
Information for Patients:
Patients using topical corticosteroids should receive the following
information and instructions:
1.This medication is to be used as directed by the physician. It is
for external use only. Avoid contact with the eyes.
2.This medication should not be used for any disorder other than
that for which it was prescribed.
3.The treated skin area should not be bandaged, otherwise covered
or wrapped, so as to be occlusive unless directed by the physician.
4.Patients should report any signs of local adverse reactions to
5.Patients should inform their physicians that they are using
Clobetasol propionate if surgery is contemplated.
Soluble in water
specific rotation[α ]D20
+6.3 o -+7.3 o
Loss on drying
Residue on ignition